ABSTRACT
This was a case of an intrauterine parvoviral B19 infection resulting in hydrops fetalis and enlarged placenta. Histologically, the virus was found to be in nucleated red cells of the fetus which was confirmed by electron microscopy. Careful placental examination at the gross and microscopic levels yielded the correct diagnosis.
Subject(s)
Adult , Female , Fetal Death , Gestational Age , Humans , Hydrops Fetalis/diagnosis , Parvoviridae Infections/complications , Parvovirus/isolation & purification , Pregnancy , Pregnancy Outcome , ThailandABSTRACT
A unique case of nosocomial aspergillosis following neurosurgery in a 10 year old girl was documented. She presented with intracerebral hemorrhage after three weeks of operation for evacuation of craniopharyngioma. To our knowledge, this is the first reported case of intracerebral hemorrhage due to nosocomial aspergillosis following neurosurgery.
Subject(s)
Brain Diseases/complications , Cerebral Hemorrhage/microbiology , Child , Craniopharyngioma/surgery , Craniotomy/adverse effects , Cross Infection/complications , Fatal Outcome , Female , Humans , Neuroaspergillosis/complications , Pituitary Neoplasms/surgery , Tomography, X-Ray ComputedABSTRACT
Most causes of death during the fetal period are still unknown in all birth weight groups. Intrauterine anoxia evidence by clinical data and autopsy finding is the leading known cause in infants 1,001-2,500 g and over 2,500 g. In the early neonatal period in infants 1,001-2,500 g and over 2,500 g, the most common cause of death is congenital malformation which was also found as the main cause in the late neonatal over 2,500 g group. More than half of the deaths in the late neonatal period 1,001-2,500 g group, were caused by infection. Congenital syphilis and tetanus neonatorum which existed in the first study were not found in this study which reflects improved medical care.
Subject(s)
Autopsy , Birth Weight , Cause of Death , Hospitals, University , Humans , Infant Mortality , Infant, Newborn , Risk Factors , Thailand/epidemiologyABSTRACT
A case of early neonatal severe bleeding and persistent hypoglycemia with a fatal outcome is reported. The autopsy examination revealed the features of neonatal hepatic necrosis. Further study by the electron microscopy indicated the presence of herpes type particles in the nucleus and cytoplasm of the remaining liver cells. Serological study of the maternal blood, post partum, revelaed positive reaction to Herpes simplex virus type 2 at low titer. It is believed that intrauterine herpes infection was responsible for the severe hepatic damage manifesting in complex clinical findings.